Assuming you really have no connection to your SIL.
I am not an expert but here is my thought.
Every person wants to be cherished, they want to feel important, they want to feel secure.
Most men are working, so they implicitly become important, their job , their status, their schedule becomes a priority around which life of others revolve.
In such cases I have seen ladies feeling neglected, they become insecure as they feel they are not equal in relationship and no one is dependent on them.
So, if she has some hobby, some craft, some education that can be utilised to get her some work/business it will relieve her of many insecurities. Take active participation in something that your wife likes.
Eg: My wife likes skin care products, I never had more than a soap & shampoo... I reasearched the products, I understood them.. now I know more than her, we do skin care together...
Also, eat well, exercise together, ample of sun - not kidding.. this can trigger some good hormones in people..
I have experienced it first hand with my wife.