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All jobsOnsiteResearchhealthtech10+ yearsorganic chemistry
OnsiteDirectorhealthtech

Head of Discovery Chemistry

A*STARSingaporePosted 20 May 2026

The Head of Discovery Chemistry at A*STAR will lead scientific and strategic efforts across small-molecule drug discovery. This role manages medicinal, computational, and peptide chemistry functions while collaborating with cross-functional teams to progress programs from ideation to nomination. Candidates must possess deep chemistry expertise and a proven track record in drug discovery and external partnership management. The position is responsible for budget management, mentorship, and representing the organization in the scientific community.

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Experience

10+ years

Function

Research

Work mode

Onsite, Singapore

Company

Tier 2

What you will work on

The Head of Discovery Chemistry at A*STAR will lead scientific and strategic efforts across small-molecule drug discovery. This role manages medicinal, computational, and peptide chemistry functions while collaborating with cross-functional teams to progress programs from ideation to nomination. Candidates must possess deep chemistry expertise and a proven track record in drug discovery and external partnership management. The position is responsible for budget management, mentorship, and representing the organization in the scientific community.

TAL's take

Quality 65/1005/5 clarityTier 2 company

Senior leadership role at a prominent research agency with clear strategic ownership and high educational requirements.

The JD is extremely well-defined, outlining specific scientific domains, cross-functional responsibilities, and strategic leadership expectations.

Must haves

  • Ph.D. in Organic Chemistry, Medicinal Chemistry, or closely related discipline
  • Minimum of 10 years of relevant drug discovery experience
  • Track record of progressing compounds through the discovery pipeline
  • Broad understanding of drug discovery beyond chemistry
  • Deep domain expertise in organic synthesis and medicinal chemistry

Tools and skills

organic chemistrymedicinal chemistrycomputational chemistrypeptide chemistryorganic synthesis

About the company

A*STAR is a significant government statutory board in Singapore, treated as a Tier 2 equivalent due to its scale and scientific influence.